Qualitative research in critical care: Has its time finally come?

Bioimpedance: Has Its Time Finally Come?

Bioimpedance, themeasurement of the frequency-dependent resistance to the flow of low energy electrical currents between two electrodes on or within the body, has been investigated for various medical applications for over 50 years. Applications in cardiology date back to at least 1966 and have included attempts to estimate stroke volume, cardiac output, cardiac contractility and lung fluid vol...

The time has (finally) come for the digital hospital.

Cancer and the circadian clock: has the time finally come?

W ithout the concept of time, there would be no physics, chemistry, or geology, but in medicine, time often gets short shrift. Yet in recent decades a small cadre of clinical investigators has found associations between the body's daily rhythms and the effectiveness of cancer treatment. Working in tandem, biologists have dissected the molecular underpinnings of the human circadian clock, a feed...

XML Databases: An Idea Whose Time has Finally Come

The demand for an efficient means to manage XML content is increasing proportionately with our increased dependence on XML-based applications, messaging and distributed computing. This white paper examines current market forces, available technology and the emerging XML landscape to gauge the value and, by extension, the demand for an XML-centric database that can sit alongside the many flavors...

Harmonization: Its Time Has Come.

The importance of standardization of laboratory test results has a long history traceable to the first proficiency testing results in 1947 that demonstrated large discrepancies among results from 59 hospital laboratories (1 ). The AACC published a series of monographs in 1953– 1972 titled Standard Methods of Clinical Chemistry that promoted a single measurement procedure (MP) for a measurand. T...